Zithromax (azithromycin) is an antibiotic used to treat bacterial infections in adults and children. It is commonly prescribed for ear and sinus infections, pneumonia, and strep throat. It is approved for children 6 months or older and is a good option for kids with penicillin allergies. Show
Commonly referred to as a Z-Pak (as a five-day course) or a Tri-Pak (as a three-day course), azithromycin also comes as a liquid for kids who are unable to swallow pills. It can be taken with or without food. This article discusses the use of azithromycin for kids. It details what Zithromax treats and pediatric dosing information. It also explains side effects and drug interactions. Azithromycin Uses for KidsThough azithromycin is approved for pediatric use, its safety and effectiveness in kids under the age of 6 months haven't been established. The drug has been approved to treat the following pediatric conditions:
Zithromax is often used off-label for other mild to moderate pediatric infections that are caused by susceptible bacteria, including walking pneumonia and pertussis (whooping cough). Zithromax is generally not used as first-line treatment unless the first-line antibiotic has failed or the child has an allergy to the preferred drug. Increasing rates of azithromycin resistance mean that the drug is generally reserved for second-line use. For strep throat, penicillin is the preferred agent. Similarly, the American Academy of Pediatrics (AAP) recommends amoxicillin as the first-line drug of choice for ear infections. Forms of Azithromycin for KidsZithromax is a type of macrolide antibiotic, a class of medications that also includes erythromycin, roxithromycin, and clarithromycin. It is a good choice for children who are allergic to penicillin. It can be taken either with or without food, often in a single dose. Zithromax has also been popular because it has always been a little less expensive than many other brand-name antibiotics, even before it became available as a generic. Zithromax is available in several forms:
Zithromax can be stored at room temperature but should be kept away from excessive heat, cold, or moisture. Do not refrigerate or freeze Zithromax, even in liquid form. If given Zithromax in powder form, mix it with water right before giving your child the dose. Zithromax Children DosagesDepending on the condition being treated, your healthcare provider will usually tailor the dose based on your child's height and weight (measured in kilograms, kg). Typical dosages include:
If you miss a dose, give it as soon as you remember unless the next dose is within 12 hours. In such a case, skip the dose and give your child the next one as you normally would. Never double up on doses as this can increase the risk of side effects. Be sure to give Zithromax exactly as prescribed, completing the entire course even if your child feels better. Failure to do so increases the risk of antibiotic resistance, making the drug far less effective the next time your child is ill. If your child vomits within an hour of taking a one-time dose, you will likely need to get another. Call your pediatrician for guidance. Azithromycin Side Effects in KidsVerywell / Brianna Gilmartin For children taking a five-day course of Zithromax, the most common side effects include:
When prescribed as a one-time dose, there is a greater risk of vomiting or diarrhea. If the side effects are severe or persistent, call your healthcare provider. On rare occasions, a child may experience a severe and potentially life-threatening allergy known as anaphylaxis. When to Call 911Call 911 or seek emergency care if your child experiences shortness of breath, wheezing, rapid heart rate, dizziness, vomiting, or swelling of the face, tongue, or throat after taking Zithromax. Azithromycin InteractionsIf your child is taking Zithromax and an antacid such as Tums, Mylanta, or Maalox, you may need to separate the doses by four hours to avoid a drop in the concentration of Zithromax in the blood. Antacids can be taken at the same time if prescribed an extended-release Zmax. Always advise your pediatrician about any and all drugs your child may be taking, whether pharmaceutical, over-the-counter, nutritional, homeopathic, or traditional. Zithromax WarningsThe U.S. Food and Drug Administration warns that azithromycin can cause changes in the heart's normal electrical activity, leading to an abnormal heart rhythm condition known as QT interval prolongation. This can cause fast and/or irregular heartbeat, severe dizziness, blurred vision, fainting, and death (rare). Certain factors can increase a child's risk while taking Zithromax:
Call your healthcare provider if your child experiences irregular heartbeats or has a sudden dizziness spell. if there is fainting, take your child to the emergency room, even if it lasted for only a few seconds. Frequently Asked Questions
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. By Vincent Iannelli, MD Thanks for your feedback! Will azithromycin treat an ear infection?Zithromax Z-PAK (azithromycin) and Augmentin (amoxicillin/clavulanate) are antibiotics used to treat bacterial infections sinusitis, pneumonia, ear infections, bronchitis, and other types of infections caused by susceptible bacteria.
How long does it take for antibiotics to fix an ear infection?How Long Does It Take for an Ear Infection to Clear Up? Many mild ear infections will clear up in two or three days. If antibiotics are prescribed, the course is usually 10 days. However, fluid in the ear may linger for a few weeks even after the infection clears up.
What is the best antibiotic for an ear infection?One of the most commonly prescribed antibiotics for ear infections is amoxicillin. However, some types of bacteria are becoming resistant to it because of its frequent, and usually unnecessary, use. Ciprofloxacin is another commonly used antibiotic for fighting bacterial ear infections.
How much azithromycin should I take for ear infection?For treatment of infections: Adults—500 to 2000 milligrams (mg) once a day, taken as a single dose. Depending on the type of infection, this may be followed with doses of 250 to 500 mg once a day for several days. Children 6 months of age and older—Dose is based on body weight and must be determined by your doctor.
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