Neomycin and polymyxin b ear drops for ear infection

  • Overview
  • Consumer Information
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Cortisporin Otic Solution Side Effects Center

What Is Cortisporin Otic Solution?

Cortisporin Otic Solution (neomycin and polymyxin B sulfates and hydrocortisone otic solution) is a combination of two antibiotics and an anti-inflammatory corticosteroid in an ear drop used to treat outer ear infections caused by bacteria (also known as swimmer's ear). Cortisporin Otic Solution is available in generic form.

What Are Side Effects of Cortisporin Otic Solution?

Common side effects of Cortisporin Otic Solution include:

  • temporary stinging or burning of the ear for a minute or two when applied.

Tell your doctor if you have a rare but very serious side effect of Cortisporin Otic Solution such as:

  • hearing problems (e.g., hearing loss).

Dosage for Cortisporin Otic Solution?

The dose of Cortisporin Otic Solution for adults is four drops instilled into the affected ear 3 or 4 times daily. For infants and children, three drops are suggested.

What Drugs, Substances, or Supplements Interact with Cortisporin Otic Solution?

Cortisporin Otic Solution may interact with other medications. Before using this medication, tell your doctor all prescription and nonprescription/herbal products you may use.

Cortisporin Otic Solution During Pregnancy and Breastfeeding

Cortisporin Otic Solution should be used only if prescribed during pregnancy. It is not known whether this medication passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Cortisporin Otic Solution (neomycin and polymyxin B sulfates and hydrocortisone otic solution, USP) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Neomycin and polymyxin b ear drops for ear infection

SLIDESHOW

Ear Infection Symptoms, Causes, and Treatment See Slideshow

Cortisporin Otic Solution Consumer Information

SIDE EFFECTS: This medication may temporarily sting or burn your ear for a minute or two when applied. If these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if this rare but very serious side effect occurs: hearing problems (e.g., hearing loss).

Use of this medication for prolonged or repeated periods may result in a new fungal ear infection. Do not use it for longer than prescribed. Contact your doctor if you notice new or worsening symptoms.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), redness of the ears, severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Neomycin and polymyxin b ear drops for ear infection

QUESTION

Ear infection or acute otitis media is an infection of the middle ear. See Answer

Cortisporin Otic Solution Professional Information

SIDE EFFECTS

Neomycin occasionally causes skin sensitization. Ototoxicity and nephrotoxicity have also been reported (see WARNINGS). Adverse reactions have occurred with topical use of antibiotic combinations including neomycin and polymyxin B. Exact incidence figures are not available since no denominator of treated patients is available. The reaction occurring most often is allergic sensitization. In one clinical study, using a 20% neomycin patch, neomycin-induced allergic skin reactions occurred in two of 2,175 (0.09%) individuals in the general population.2 In another study, the incidence was found to be approximately 1%.3

The following local adverse reactions have been reported with topical corticosteroids, especially under occlusive dressings: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. Stinging and burning have been reported when this product has gained access to the middle ear.

Read the entire FDA prescribing information for Cortisporin Otic Solution (Neomycin and Polymyxin B Sulfates and Hydrocortisone Otic Solution)

© Cortisporin Otic Solution Patient Information is supplied by Cerner Multum, Inc. and Cortisporin Otic Solution Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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How long does it take for neomycin polymyxin ear drops to work?

Hydrocortisone - neomycin - polymyxin B ear drops are used to treat certain bacterial infections of the outer ear canal. This medication should start to work within 48 hours.

How long do you leave neomycin in your ear?

Drop the prescribed number of drops into the ear canal. Keep the ear facing up for about 5 minutes to allow the medicine to coat the ear canal. (For young children and other patients who cannot stay still for 5 minutes, try to keep the ear facing up for at least 1 or 2 minutes.)

How long does it take for eardrops to work for ear infection?

Once I start using the eardrops how long should it take until I feel better? Most people feel better within 48 to 72 hours and have minimal or no symptoms by 7 days. Notify your doctor if your pain or other symptoms fail to respond within this time frame.

What is the best antibiotic for a ear infection?

One of the most commonly prescribed antibiotics for ear infections is amoxicillin. However, some types of bacteria are becoming resistant to it because of its frequent, and usually unnecessary, use. Ciprofloxacin is another commonly used antibiotic for fighting bacterial ear infections.