Journal of pharmaceutical research international impact factor

1.

VARIOUS HERBAL PLANTS ARE USED AS ANTICANCER AGENTS

Cancer is the world's second-largest cause of death. Although substantial progress has been made in treating and controlling cancer progression, there are still significant flaws and space for improvement. During chemotherapy, several unfavourable side effects might arise. Natural-derived substances are attracting scientific and academic attention since they are thought to have fewer hazardous sid...

C. Sangavi * and R. Senthamarai

Department of Pharmaceutics, Periyar College of Pharmaceutical Sciences, Tiruchirappalli, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).3807-23

3807-3823

2.

A SYSTEMATIC REVIEW OF AN INVASIVE PLANT SPECIES: VERBESINA ENCELIOIDES (CAV.) BENTH. & HOOK. F. EX A. GRAY

An introduced, non-native, exotic, or alien species are those that grow in areas outside of their natural habitats. They get introduced deliberately or accidentally into new areas by anthropogenic activities or naturally through water, wind, etc. In non-native areas, these species invade rapidly due to the non-availability of natural enemies (prey) in a new habitat. Therefore, these fast-spreading...

Kuljinder Kaur *, M. C. Sidhu and A. S. Ahluwalia

DOI: 10.13040/IJPSR.0975-8232.13(10).3824-32

3824-3832

3.

A WAY OF COMBATING ANTIMICROBIAL RESISTANCE THROUGH QUORUM SENSING

Quorum sensing is a peculiar mechanism of microbial communication through the induction of various signalling autoinducer molecules having several gene expression regulatory activities of different virulence factors that control microbial. This enables a systematic path of inhibiting microbial growth and its infection production efficacy by indirectly regulating the Quorum sensing activity of the ...

Shabnam Thakur *, Rupali Sharma and Rakesh Yadav

Amity Institute of Pharmacy, Amity University Haryana, Manesar, Gurgaon, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).3833-40

3833-3840

4.

EFFECT OF PARATHYROID HORMONE LEVELS ON PERIODONTAL STATUS IN PREGNANT WOMEN: A REVIEW

Periodontitis is a multifactorial disease. It has several associations with hormonal fluctuations; the body undergoes several physiological hormonal mechanisms. In several physiological conditions, hormonal fluctuations have been observed. One such condition is pregnancy. Several hormones are at play during pregnancy; one such hormone is PTH. Parathyroid hormone is essential to increase the matern...

Aditi Chaturvedi, Vidushi Sheokand *, Amit Bhardwaj, Anurag Bhatnagar, Alisha Chugh, Megha Tomar and Kevin Raj

Department of Periodontology, SGT Dental College and Research Centre, Gurugram, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).3841-44

3841-3844

5.

A REVIEW ON PREPARATION & METHODS OF CURCUMIN NANOPARTICLES AND ITS APPLICATION

Curcumin is a highly potent, nontoxic, bioactive agent found in turmeric and has been known for centuries as a household remedy to many ailments. The main active ingredient of turmeric is curcumin, a polyphenol that helps prevent and control neurological, respiratory, cardiovascular, metabolic, inflammatory and autoimmune diseases and some cancers. The major drawbacks of curcumin are low absorptio...

Vijaya Lakshmi Jampala *, Swarupa Arvapalli

Joginpally B. R. Pharmacy College, Moinabad, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).3845-56

3845-3856

12.

ANTIAPOPTOTIC MECHANISM FOR THE IMPLEMENTATION OF THE HEPATOPROTECTIVE EFFECT OF PYRIMIDINE DERIVATIVES

The present study aimed to study the effect of the drug Xymedon and its conjugate with L-ascorbic acid exhibiting hepatoprotective activity on the apoptosis of rat liver cells against the background of the influence of hepatotoxic agent tetrachloromethane. Though the general effects of Xymedon and its conjugates with various biogenic acids have been studied, the molecular markers affected by the c...

A. A. Parfenov , A. B. Vyshtakalyuk *, I. V. Galyametdinova, V. E. Semenov and V. V. Zobov

Institute of Fundamental Medicine and Biology of Kazan Federal University, 5 Tovarisheskaya Str., Kazan, Russia.

DOI: 10.13040/IJPSR.0975-8232.13(10).39231

3922-3931

13.

EFFECT OF AQUEOUS EXTRACT OF CRYPTOLEPIS SANGUINOLENTA ADMINISTRATION ON THE METABOLISM OF CHLOROQUINE VIA CYTOCHROME P450 ISOZYMES

Concurrent administration of herbal medicines and conventional drugs is a common practice globally, especially as the patronage of medicinal plants increases across the world. This study aimed to determine the effect of Cryptolepis sanguinolenta administration on the metabolism of chloroquine by evaluating specific Cytochrome P450 isozymes. Reconstituted freeze dried Cryptolepis sanguinolenta was ...

M. M. Sakyiamah

Phytochemistry Department, Centre for Plant Medicine Research (CPMR), P.O. Box 73, Mampong-Akuapem, E/R, Ghana.

DOI: 10.13040/IJPSR.0975-8232.13(10).3932-39

3932-3939

14.

INVESTIGATING AND SEQUENCING OF THIOL-SPECIFIC ANTIOXIDANT GENE IN A SYRIAN STRAIN OF LEISHMANIA TROPICA

Cutaneous leishmania is a common medical problem in Syria, which has become yet more widespread in most of the Syrian governorates after the current war. An effective vaccine is needed to prevent a large scale spread of leishmaniasis in the country. In this regard, protein vaccination has shown promising prospects of creating this much-needed vaccine. Thiol Specific Antioxident (TSA) plays a funda...

Hassan Al. Khouri * and Shaden Haddad

Department of Biochemestry and Microbiology, Damascus University, Damascus Syria.

DOI: 10.13040/IJPSR.0975-8232.13(10).3940-43

3940-3943

15.

NEUROTHERAPEUTIC EFFECT OF BERGENIN ON CUPRIZONE-INDUCED DEMYELINATION BY REGULATING NEUROLOGICAL FUNCTIONS ASSOCIATED WITH MOTOR ACTIVITY, OXIDATIVE STRESS, AND HISTOLOGICAL ALTERATIONS IN THE CORPUS CALLOSUM OF C57BL/6 MICE

Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system characterized by Neuroinflammation, oligodendrocyte loss, and axonal pathology. Bergenin, a chief phytochemical constituent of Bergenia species, has been shown to exert anti-inflammatory and antioxidant effects. The cuprizone (CPZ) model is an established mouse model of MS and causes demyelination and induces ...

Akila Murugan and Sumathi Thangarajan *

Department of Medical Biochemistry, Dr. A. L. M Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).3944-52

3944-3952

16.

A TRAILBLAZING ENDEAVOUR TO EXPLORE THE ROLE OF TULASI PUSHPA AS SANDHANA DRAVYA (FERMENTING AGENT) IN SANDHANA KALPANA

Sandhāna kalpanā (Fermentation process) is a unique procedure implemented in Ayurveda for the preparation of fermented alcoholic and acidic medicinal formulations. Sandhāna dravyās (fermenting agents) act as fermentation initiators in them. The commonly used Sandhāna dravyās are Dhātakipuṣpā (flowers of Woodfordia fruticosa), madhūkapuṣpā (flowers of Madhuka indica) and yeast. Almost...

Aansu Susan Varghese *, N. K. Sangeetha Nandakumar, Abhayakumar Mishra, Arun Mohanan, P. K. Vineeth and N. V. Ramesh

Department of Rasashastra and Bhaishajya Kalpana (Medicinal Chemistry and Pharmacy), Amrita School of Ayurveda, Amritapuri, Amrita Vishwa Vidyapeetham, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.13(10).3953-59

3953-3959