What research is being done? The NINDS supports research on disorders of the brain, spinal cord, and peripheral nerves that can cause
paresthesia. The goals of this research are to increase scientific understanding of these disorders and to find ways to prevent, treat, and cure them. Information from the National Library of Medicine’s MedlinePlus
Definition Definition Paresthesia refers to a burning or prickling sensation that is
usually felt in the hands, arms, legs, or feet, but can also occur in other parts of the body. The sensation, which happens without warning, is usually painless and described as tingling or numbness, skin crawling, or itching. Most people have experienced temporary paresthesia -- a feeling of "pins and needles" -- at some time in their lives when they have sat with legs crossed for too long, or fallen asleep with an arm crooked under their head. It happens when sustained pressure is placed
on a nerve. The feeling quickly goes away once the pressure is relieved. Chronic paresthesia is often a symptom of an underlying neurological disease or traumatic nerve damage. Paresthesia can be caused by disorders affecting the central nervous system, such as stroke and transient ischemic attacks (mini-strokes), multiple sclerosis, transverse myelitis, and encephalitis. A tumor or vascular lesion pressed up against the brain or spinal cord can also cause paresthesia. Nerve entrapment
syndromes, such as carpal tunnel syndrome, can damage peripheral nerves and cause paresthesia accompanied by pain. Diagnostic evaluation is based on determining the underlying condition causing the paresthetic sensations. An individual's medical history, physical examination, and laboratory tests are essential for the diagnosis. Physicians may order additional tests depending on the suspected cause of the paresthesia. Read More Read Less
Treatment Treatment The appropriate treatment for paresthesia depends on accurate diagnosis of the underlying cause. Prognosis Prognosis The prognosis for those with paresthesia depends on the severity of the sensations and the associated disorders. Clinical Trials Clinical Trials OverviewPeripheral neuropathy, a result of damage to the nerves located outside of the brain and spinal cord (peripheral nerves), often causes weakness, numbness and pain, usually in the hands and feet. It can also affect other areas and body functions including digestion, urination and circulation. Your peripheral nervous system sends information from your brain and spinal cord (central nervous system) to the rest of your body. The peripheral nerves also send sensory information to the central nervous system. Peripheral neuropathy can result from traumatic injuries, infections, metabolic problems, inherited causes and exposure to toxins. One of the most common causes is diabetes. People with peripheral neuropathy generally describe the pain as stabbing, burning or tingling. In many cases, symptoms improve, especially if caused by a treatable condition. Medications can reduce the pain of peripheral neuropathy. SymptomsEvery nerve in your peripheral system has a specific function, so symptoms depend on the type of nerves affected. Nerves are classified into:
Signs and symptoms of peripheral neuropathy might include:
If autonomic nerves are affected, signs and symptoms might include:
Peripheral neuropathy can affect one nerve (mononeuropathy), two or more nerves in different areas (multiple mononeuropathy), or many nerves (polyneuropathy). Carpal tunnel syndrome is an example of mononeuropathy. Most people with peripheral neuropathy have polyneuropathy. When to see a doctorSeek medical care right away if you notice unusual tingling, weakness or pain in your hands or feet. Early diagnosis and treatment offer the best chance for controlling your symptoms and preventing further damage to your peripheral nerves. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. CausesPeripheral neuropathy is nerve damage caused by a number of different conditions. Health conditions that can cause peripheral neuropathy include:
Other causes of neuropathies include:
In a number of cases, no cause can be identified (idiopathic). Risk factorsPeripheral neuropathy risk factors include:
ComplicationsComplications of peripheral neuropathy can include:
PreventionManage underlying conditionsThe best way to prevent peripheral neuropathy is to manage medical conditions that put you at risk, such as diabetes, alcoholism or rheumatoid arthritis. Make healthy lifestyle choicesThese habits support your nerve health:
Aug. 11, 2022 What illness causes pins and needles?Paresthesia can be caused by disorders affecting the central nervous system, such as stroke and transient ischemic attacks (mini-strokes), multiple sclerosis, transverse myelitis, and encephalitis. A tumor or vascular lesion pressed up against the brain or spinal cord can also cause paresthesia.
When should I be concerned about pins and needles?Persistent pins and needles may be symptomatic of more serious conditions, such as nerve injury or inflammation. Always see your doctor if you experience persistent or frequent episodes of pins and needles.
What does pins and needles indicate?It's a sign that a nerve is irritated and sending extra signals. Think of that pins and needles feeling as a traffic jam in your nervous system. When traffic is running smoothly, tiny electrical impulses move along the nerves that run from your spine to your arms and legs.
Why do random parts of my body get pins and needles?Pressure on peripheral nerves from enlarged blood vessels, tumors, scar tissue, or infection. Shingles or herpes zoster infection. Other infections such as HIV/AIDS, leprosy, syphilis, or tuberculosis. Lack of blood supply to an area, such as from hardening of the arteries, frostbite, or vessel inflammation.
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